Tyzoon Nomanbhoy
Company: Vicinitas Therapeutics
Job title: Vice President, Chemical Biology
Seminars:
Utilization of Mass Spectrometry to Efficiently Identify & Validate DUB Recruiters & DUBTACs 10:00 am
day: Day One
Identifying Novel Protein Partners for DUBTACs to Expand the Viable Targets for Stabilization & Restoring Protein Function in New Disease Paradigms 1:05 pm
DUBTACs present a vastly developing paradigm of induced proximity modalities with therapeutic utility for disorders linked to perturbed ubiquitin signaling, such as oncology and neurodegenerative conditions. Despite offering a novel avenue to modulate ubiquitin homeostasis beyond degradation, clinically relevant targets have yet to gain proof of concept. Attaining selective DUB and E3 ligase pairs confronts…Read more
day: Pre-Conference Day