4th Annual Induced Proximity-Based Drug Discovery Summit

As PROTACs continue to advance, there remains a vast frontier of untapped potential in heterobifunctional and monovalent approaches, extending beyond the ubiquitin proteasome system. This uncharted territory is attracting new and distinguished players in the biopharmaceutical arena, all competing to pioneer advancements in targeted stabilization, modulation, post-translational modification, and inactivation/activation modalities.

Navigating this emerging proximity phenomenon presents considerable challenges, including persisting knowledge gaps in validating novel mechanisms of action, accessing diverse chemical matter, and designing selective and potent small molecules and biologics for novel target spaces.

The 4th Annual Induced Proximity-Based Drug Discovery Summit returned as the definitive and longest-standing forum dedicated to demonstrating the feasibility of protein stabilization, modulation, and post-translational modification.

As the community makes early breakthroughs, attendees joined us to address their pressing questions through data-driven presentations, technical discussions, and interactive sessions. We brought together over 60 induced proximity experts committed to exploring the application of induced proximity across diverse fields, both within and beyond protein degradation.