Tyzoon Nomanbhoy

Company: Vicinitas Therapeutics

Job title: Vice President, Chemical Biology

Seminars:

Utilization of Mass Spectrometry to Efficiently Identify & Validate DUB Recruiters & DUBTACs 10:00 am

Download the Full Event Guide to see session detailsRead more

day: Day One

Identifying Novel Protein Partners for DUBTACs to Expand the Viable Targets for Stabilization & Restoring Protein Function in New Disease Paradigms 1:05 pm

DUBTACs present a vastly developing paradigm of induced proximity modalities with therapeutic utility for disorders linked to perturbed ubiquitin signaling, such as oncology and neurodegenerative conditions. Despite offering a novel avenue to modulate ubiquitin homeostasis beyond degradation, clinically relevant targets have yet to gain proof of concept. Attaining selective DUB and E3 ligase pairs confronts…Read more

day: Pre-Conference Day