Christian Münch
Company: Goethe University Frankfurt
Job title: Professor & Director of Proteomics
Seminars:
Identifying Novel Protein Partners for DUBTACs to Expand the Viable Targets for Stabilization & Restoring Protein Function in New Disease Paradigms 1:05 pm
DUBTACs present a vastly developing paradigm of induced proximity modalities with therapeutic utility for disorders linked to perturbed ubiquitin signaling, such as oncology and neurodegenerative conditions. Despite offering a novel avenue to modulate ubiquitin homeostasis beyond degradation, clinically relevant targets have yet to gain proof of concept. Attaining selective DUB and E3 ligase pairs confronts…Read more
day: Pre-Conference Day