Showcasing the EpiTAC Platform to Optimizing the Clearance of Membrane & Extracellular Targets
Time: 11:30 am
Details:
- What are the molecular mechanisms underlying degradation of extracellular proteins and how can these be modulated by bispecific antibodies for optimal protein clearance?
- How to define a suitable target for induced degradation?
- What are the key design principles for effective EpiTAC bispecific antibodies?
- How is the degradation activity of EpiTACs monitored? How to minimize off-target effects?