Optimizing Induced Proximity Labeling Techniques to Accurately Measure Induced Proximity Interactions In-Cell for Improved Translational Outcomes

Time: 11:00 am
day: Day One

Details:

  • How to optimize in-cell assays to assess permeability, intracellular stability and functional engagement for ensuring efficacy in complex biological environments?
  • How to improve assay scalability in routine use for more cost-effective, high-throughput alternatives to de-risk early-stage development and improve translation?
  • How can advanced proximity-labeling methods (e.g., TurboID, MicroMap) improve resolution in mapping real-time protein interactomes to refine MoA validation for selecting the most clinically viable therapeutic candidates?

Speakers: