Optimizing Induced Proximity Labeling Techniques to Accurately Measure Induced Proximity Interactions In-Cell for Improved Translational Outcomes
Time: 11:00 am
day: Day One
Details:
- How to optimize in-cell assays to assess permeability, intracellular stability and functional engagement for ensuring efficacy in complex biological environments?
- How to improve assay scalability in routine use for more cost-effective, high-throughput alternatives to de-risk early-stage development and improve translation?
- How can advanced proximity-labeling methods (e.g., TurboID, MicroMap) improve resolution in mapping real-time protein interactomes to refine MoA validation for selecting the most clinically viable therapeutic candidates?