Harnessing tPRIME (Targeted PRoximity Induced Modulator of Expression) with Transcription Factors to Enable Fine-Tuned Gene Expression Control & Unlock New Therapeutic Modalities
Time: 1:30 pm
day: Day One
Details:
- How can tPRIME be leveraged to enhance transcriptional regulation, ensuring more precise and sustained target activation for therapeutic benefit?
- What structural and molecular determinants drive the success of tPRIME in selectively stabilizing transcription factors without off-target effects?
- How can tPRIME be applied across different disease models to expand druggable space and overcome limitations in targeting transcription factors with traditional small molecules?