Kevin Foley

Kevin Foley

Company: Ranok Therapeutics

Job title: CSO


Tumor-Targeted Protein Degradation Mediated by Cellular Chaperones 3:45 pm

Chaperones can direct not only the correct folding of proteins, but also their degradation via the ubiquitin-proteasome system Chemically inducing proximity between a drug target and the cellular chaperone machinery results in its degradation, which is mediated by the numerous E3 ligases associated with chaperone complexes Chaperone-mediated protein degradation (CHAMP™) has a number of advantages,…Read more

day: Day One

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