Kevin Foley

Kevin Foley

Company: Ranok Therapeutics Co. Ltd.

Job title: Chief Scientific Officer

Seminars:

Live Presenter Q&A 9:50 am

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day: Day Two

Tumor-Targeted Protein Degradation Mediated by Cellular Chaperones 9:25 am

Chaperones can direct not only the correct folding of proteins, but also their degradation via the ubiquitin-proteasome system Chemically inducing proximity between a drug target and the cellular chaperone machinery results in its degradation, which is mediated by the numerous E3 ligases associated with chaperone complexes Chaperone-mediated protein degradation (CHAMP™) has a number of advantages,…Read more

day: Day Two

Panel Discussion: Advancing the Discovery of Proximity-Based Medicines 9:00 am

What needs to be done to make induced proximity a realistic therapeutic modality? What are the key challenges holding back the progress of the field? What are the most promising compounds in development?Read more

day: Day One

Live Presenter Q&A 12:20 pm

Ask the speakers your most burning questions!Read more

day: Day One

Chair’s Opening Remarks 8:50 am

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day: Day One

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