Kevin Foley
Company: Ranok Therapeutics Co. Ltd.
Job title: Chief Scientific Officer
Seminars:
Live Presenter Q&A 9:50 am
day: Day Two
Tumor-Targeted Protein Degradation Mediated by Cellular Chaperones 9:25 am
Chaperones can direct not only the correct folding of proteins, but also their degradation via the ubiquitin-proteasome system Chemically inducing proximity between a drug target and the cellular chaperone machinery results in its degradation, which is mediated by the numerous E3 ligases associated with chaperone complexes Chaperone-mediated protein degradation (CHAMP™) has a number of advantages,…Read more
day: Day Two
Panel Discussion: Advancing the Discovery of Proximity-Based Medicines 9:00 am
What needs to be done to make induced proximity a realistic therapeutic modality? What are the key challenges holding back the progress of the field? What are the most promising compounds in development?Read more
day: Day One
Live Presenter Q&A 12:20 pm
Ask the speakers your most burning questions!Read more
day: Day One
Chair’s Opening Remarks 8:50 am
day: Day One