Katarina Pance

Katarina Pance

Company: University of California, San Francisco

Job title: PhD Candidate (Jim Wells Lab)


Targeted Degradation of Extracellular Proteins Using Antibody-Based Biologics 4:45 pm

Targeted protein degradation is an established new modality for drug discovery for intracellular proteins, yet most small molecule and biologics engage extracellular targets We have recently shown it possible to degrade therapeutically relevant membrane proteins by recruiting transmembrane E3 ligases to proteins of interest using bi-specific antibodies, a biologics technology akin to small molecule PROTACs,…Read more

day: Day One

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