Linking Structure to Function for Heterobifunctionals: Structural Considerations that Affect Function

Time: 2:00 pm
day: Conference Day One


  • Utilizing steric considerations to promote the interaction between protein of interest and effector machinery
  • Using linker size and chemistry to positively affect heterobifunctional design and function
  • How to optimize heterobifunctional structure for increased membrane solubility and oral drug availability