Linking Structure to Function for Heterobifunctionals: Structural Considerations that Affect Function
Time: 2:00 pm
day: Conference Day One
Details:
- Utilizing steric considerations to promote the interaction between protein of interest and effector machinery
- Using linker size and chemistry to positively affect heterobifunctional design and function
- How to optimize heterobifunctional structure for increased membrane solubility and oral drug availability
